Results 41 to 50 of about 356,368 (214)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Effect of temperature and dissolved oxygen on metabolic rate and survival rate of larvae green catfish (Mystus nemurus Cuv. & Val.)

open access: yesJournal of Biological Researches, 2000
The rearing technology of green catfish larvae has not yet established. Hight mortality occurred in the early larval stages. This experiment was conducted to study the effect of temperature and dissolved oxygen on metabolic rate and survival rate of ...
Usman Muhammad Tang   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Ion fluxes in silver catfish (Rhamdia quelen) juveniles exposed to different dissolved oxygen levels

open access: yesNeotropical Ichthyology
Low dissolved oxygen levels in the water (hypoxia) can be provoked by oxygen consumption by fish and other organisms, organic matter decomposition, phytoplankton blooms, and temperature increase. The objective of the present study was to investigate Na+,
Felipe Link de Rosso   +2 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

A hybrid intelligent method for three-dimensional short-term prediction of dissolved oxygen content in aquaculture. [PDF]

open access: yesPLoS ONE, 2018
A precise predictive model is important for obtaining a clear understanding of the changes in dissolved oxygen content in crab ponds. Highly accurate interval forecasting of dissolved oxygen content is fundamental to reduce risk, and three-dimensional ...
Yingyi Chen   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Dissolved Oxygen Regulatory System Using Fuzzy Logic Method Based on Teensy Board Microcontroller

open access: yesJAREE (Journal on Advanced Research in Electrical Engineering), 2019
Dissolved oxygen in water becomes a critical factor in the cultivation of fish hatcheries that determines the success/failure rate in the process of improving the quality and quantity of fish hatcheries. Low dissolved oxygen levels cause deficient to the
Fajar Budiman   +3 more
doaj  

Artificially decreased dissolved oxygen increases the persistence of Trichomonas gallinae in water

open access: yesInternational Journal for Parasitology: Parasites and Wildlife, 2019
Water containing organic material has been shown to increase the persistence of the avian pathogenic protozoa, Trichomonas gallinae. We hypothesized that the decrease in dissolved oxygen due to microbes in the organic material could increase persistence ...
Kathryn Purple   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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