Results 51 to 60 of about 39,337 (267)
Characteristics studies of molecular structures in drugs
Saudi Pharmaceutical Journal, 2017 In theoretical medicine, topological indices are defined to test the medicine and pharmacy characteristics, such as melting point, boiling point, toxicity and other biological activities.
Wei Gao +3 more
doaj +1 more source
Shilla distance-regular graphs
European Journal of Combinatorics, 2010 14 ...
Koolen, JH, Park, J
openaire +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
ENUMERATION INTERSECTION ARRAYS OF SHILLA GRAPHS WITH B = 6
Ural Mathematical JournalLet \(\Gamma\) be a distance-regular graph of diameter \(3\), and let \(\theta_1\) be its second eigenvalue. The graph \(\Gamma\) is called a Shilla graph if \(\theta_1=a_3\). In this case, \(\theta_1={(a_1+\sqrt{a_1^2+4k})}/{2}\), and \(a=a_3\) divides \
Alexander A. Makhnev +2 more
doaj +1 more source
Electronic Journal of Graph Theory and Applications, 2015 The reciprocal complementary distance (RCD) matrix of a graph $G$ is defined as $RCD(G) = [rc_{ij}]$ where $rc_{ij} = \frac{1}{1+D-d_{ij}}$ if $i \neq j$ and $rc_{ij} = 0$, otherwise, where $D$ is the diameter of $G$ and $d_{ij}$ is the distance between ...
Harishchandra S. Ramane +1 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Novel Description on Vague Graph with Application in Transportation Systems
Journal of Mathematics, 2021 Fuzzy graph (FG) models embrace the ubiquity of existing in natural and man-made structures, specifically dynamic processes in physical, biological, and social systems.
Zheng Kou, Saeed Kosari, Maryam Akhoundi
doaj +1 more source
Regular handicap graphs of order n ≡ 4 (mod 8)
Electronic Journal of Graph Theory and Applications, 2022 A handicap distance antimagic labeling of a graph G = (V, E) with n vertices is a bijection f : V → {1, 2, …, n} with the property that f(xi)=i, the weight w(xi) is the sum of labels of all neighbors of xi, and the sequence of the weights w(x1),w(x2),…,w(
Dalibor Froncek, Aaron Shepanik
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source