Results 71 to 80 of about 542,793 (319)

Characteristics studies of molecular structures in drugs

open access: yesSaudi Pharmaceutical Journal, 2017
In theoretical medicine, topological indices are defined to test the medicine and pharmacy characteristics, such as melting point, boiling point, toxicity and other biological activities.
Wei Gao   +3 more
doaj   +1 more source

The subconstituent algebra of a distance-regular graph; thin modules with endpoint one

open access: yes, 2002
We consider a distance-regular graph Γ with diameter D⩾3, intersection numbers ai,bi,ci and eigenvalues θ0>θ1>⋯>θD. Let X denote the vertex set of Γ and fix x∈X.
Paul M. Terwilliger
semanticscholar   +1 more source

The subconstituent algebra of a bipartite distance-regular graph; thin modules with endpoint two [PDF]

open access: yesDiscrete Mathematics, 2006
We consider a bipartite distance-regular graph @C with diameter D>=4, valency k>=3, intersection numbers b"i,c"i, distance matrices A"i, and eigenvalues @q"0>@q"1>...>@q"D. Let X denote the vertex set of @C and fix x@?X.
Mark S. MacLean, Paul M. Terwilliger
semanticscholar   +1 more source

Shilla distance-regular graphs

open access: yesEuropean Journal of Combinatorics, 2010
14 ...
Koolen, JH, Park, J
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ENUMERATION INTERSECTION ARRAYS OF SHILLA GRAPHS WITH B = 6

open access: yesUral Mathematical Journal
Let \(\Gamma\) be a distance-regular graph of diameter \(3\), and let \(\theta_1\) be its second eigenvalue. The graph \(\Gamma\) is called a Shilla graph if \(\theta_1=a_3\). In this case, \(\theta_1={(a_1+\sqrt{a_1^2+4k})}/{2}\), and \(a=a_3\) divides \
Alexander A. Makhnev   +2 more
doaj   +1 more source

Reciprocal complementary distance spectra and reciprocal complementary distance energy of line graphs of regular graphs

open access: yesElectronic Journal of Graph Theory and Applications, 2015
The reciprocal complementary distance (RCD) matrix of a graph $G$ is defined as $RCD(G) = [rc_{ij}]$ where $rc_{ij} = \frac{1}{1+D-d_{ij}}$ if $i \neq j$ and $rc_{ij} = 0$, otherwise, where $D$ is the diameter of $G$ and $d_{ij}$ is the distance between ...
Harishchandra S. Ramane   +1 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

A short proof of the odd-girth theorem [PDF]

open access: yes, 2012
Recently, it has been shown that a connected graph $\Gamma$ with $d+1$ distinct eigenvalues and odd-girth $2d+1$ is distance-regular. The proof of this result was based on the spectral excess theorem.
Fiol, Miquel Angel, van Dam, Edwin R.
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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