Results 51 to 60 of about 42,350 (268)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
ON SOME VERTEX-TRANSITIVE DISTANCE-REGULAR ANTIPODAL COVERS OF COMPLETE GRAPHS
Ural Mathematical Journal, 2022 In the present paper, we classify abelian antipodal distance-regular graphs \(\Gamma\) of diameter 3 with the following property: \((*)\) \(\Gamma\) has a transitive group of automorphisms \(\widetilde{G}\) that induces a primitive almost simple ...
Ludmila Yu. Tsiovkina
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
ENUMERATION INTERSECTION ARRAYS OF SHILLA GRAPHS WITH B = 6
Ural Mathematical JournalLet \(\Gamma\) be a distance-regular graph of diameter \(3\), and let \(\theta_1\) be its second eigenvalue. The graph \(\Gamma\) is called a Shilla graph if \(\theta_1=a_3\). In this case, \(\theta_1={(a_1+\sqrt{a_1^2+4k})}/{2}\), and \(a=a_3\) divides \
Alexander A. Makhnev +2 more
doaj +1 more source
Characteristics studies of molecular structures in drugs
Saudi Pharmaceutical Journal, 2017 In theoretical medicine, topological indices are defined to test the medicine and pharmacy characteristics, such as melting point, boiling point, toxicity and other biological activities.
Wei Gao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Electronic Journal of Graph Theory and Applications, 2015 The reciprocal complementary distance (RCD) matrix of a graph $G$ is defined as $RCD(G) = [rc_{ij}]$ where $rc_{ij} = \frac{1}{1+D-d_{ij}}$ if $i \neq j$ and $rc_{ij} = 0$, otherwise, where $D$ is the diameter of $G$ and $d_{ij}$ is the distance between ...
Harishchandra S. Ramane +1 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
A flocking algorithm for multi-agent systems with connectivity preservation under hybrid metric-topological interactions. [PDF]
PLoS ONE, 2018 In this paper, we propose a connectivity-preserving flocking algorithm for multi-agent systems in which the neighbor set of each agent is determined by the hybrid metric-topological distance so that the interaction topology can be represented as the ...
Chenlong He, Zuren Feng, Zhigang Ren
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source