Results 41 to 50 of about 321,891 (280)

The spectral excess theorem for distance-regular graphs having distance-d graph with fewer distinct eigenvalues [PDF]

open access: yes, 2015
Let G be a distance-regular graph with diameter d and Kneser graph K=Gd, the distance-d graph of G. We say that G is partially antipodal when K has fewer distinct eigenvalues than G. In particular, this is the case of antipodal distance-regular graphs (K
Fiol Mora, Miquel Àngel
core   +3 more sources

On a version of the spectral excess theorem

open access: yesElectronic Journal of Graph Theory and Applications, 2020
Given a regular (connected) graph G=(X,E) with adjacency matrix A, d+1 distinct eigenvalues, and diameter D, we give a characterization  of when its distance matrix AD is a polynomial in A, in terms of the adjacency spectrum of G and the arithmetic (or ...
Miquel Àngel Fiol, Safet Penjic
doaj   +1 more source

Asymptotic Delsarte cliques in distance-regular graphs [PDF]

open access: yes, 2015
We give a new bound on the parameter $\lambda$ (number of common neighbors of a pair of adjacent vertices) in a distance-regular graph $G$, improving and generalizing bounds for strongly regular graphs by Spielman (1996) and Pyber (2014).
Babai, László, Wilmes, John
core   +2 more sources

Locally Pseudo-Distance-Regular Graphs

open access: yesJournal of Combinatorial Theory, Series B, 1996
The concept of local pseudo-distance-regularity, introduced in this paper, can be thought of as a natural generalization of distance-regularity for non-regular graphs. Intuitively speaking, such a concept is related to the regularity of graph \(\Gamma\) when it is seen from a given vertex.
Fiol, M.A., Garriga, E., Yebra, J.L.A.
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Distance-regular antipodai covering graphs

open access: yesJournal of Combinatorial Theory, Series B, 1988
Let G be a regular graph with diameter d. G is said to be antipodal if given any distinct vertices u, v, w of G with v and w at distance d from u, then v is distance d from w. G is called distance-regular if for vertices u, v, in G of distance i apart, v is adjacent to \(c_ i\) vertices distance i-1 from u, \(a_ i\) vertices distance i from u, and \(b_
Aldred, R.E.L, Godsil, C.D
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

D-bounded Distance-regular Graphs

open access: yesEuropean Journal of Combinatorics, 1997
Let \(\Gamma\) be a distance-regular graph of diameter \(D\geq 3\). The paper gives all basic facts from the literature and all necessary notions, e.g. the notion of weak-geodetically closed subgraph of \(\Gamma\), the notion of \(D\)-bounded graph, etc. Let \(P(\Gamma)\) denote the poset the elements of which are the weak-geodetically closed subgraphs
openaire   +3 more sources

Parallelogram-Free Distance-Regular Graphs

open access: yesJournal of Combinatorial Theory, Series B, 1997
This paper deals with distance-regular graphs. It is shown that a distance-regular graph with certain properties has classical parameters \((d,b,\alpha,\beta)\) with ...
Liang, Yuh-jeng, Weng, Chih-wen
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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