Results 81 to 90 of about 3,065 (300)

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

CF-RIP: a convergence-free mechanism for RIP protocol

open access: yesTongxin xuebao, 2010
In order to solve the problem of distance vector routing protocol converge very slowly to the correct routes when link costs increase,a new convergence-free routing protocol CF-RIP using RIP(routing information protocol) was proposed,which is based on ...
WANG Bin1   +3 more
doaj   +2 more sources

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

open access: yesAdvanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen   +7 more
wiley   +1 more source

Performance Evaluation of Routing Metrics in the LOADng Routing Protocol

open access: yesJournal of Communications Software and Systems, 2017
LOADng (Lightweight On-demand Ad hoc Distance-vector Routing Protocol - Next Generation) is an emerging routing protocol that emerged as an alternative to RPL (IPv6 Routing Protocol for Low power and Lossy Networks). Although some work has been dedicated
Jose V. V. Sobral   +4 more
doaj  

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao   +13 more
wiley   +1 more source

Energy Consumption Evaluation for Mobile Ad Hoc Routing Protocols

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2017
Rapidly developing wireless network technology has been continued to become the most popular research field for a couple of years. Mobile Ad hoc Network (MANET), which is a type of a wireless network, is formed by mobile nodes.
Belma Korkuter   +2 more
doaj   +1 more source

Enhanced Ad-Hoc on Demand Multipath Distance Vector Routing protocol

open access: yes, 2010
IEEE Publication format, ISSN 1947 5500, http://sites.google.com/site/ijcsis/
Mallapur, Sujata V., Terdal, Sujata
openaire   +2 more sources

Performance Analysis of AD-HOC on-Demand Distance Vector Routing Protocol

open access: yesIndian Journal of Science and Technology, 2016
Background/objectives: The performance of the Ad-hoc On-demand Distance Vector routing protocol is analyzed by simulation in this paper. Method/Statistical Analysis: The simulation is developed employing the libraries provided by the simulator. The simulation is developed to model the communication of multimedia packets in an ad hoc wireless network
N. M. Balamurugan   +1 more
openaire   +1 more source

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