Results 41 to 50 of about 5,633 (238)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Vertices Contained In All Or In No Minimum Semitotal Dominating Set Of A Tree

open access: yesDiscussiones Mathematicae Graph Theory, 2016
Let G be a graph with no isolated vertex. In this paper, we study a parameter that is squeezed between arguably the two most important domination parameters; namely, the domination number, γ(G), and the total domination number, γt(G). A set S of vertices
Henning Michael A., Marcon Alister J.
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Eternal distance-2 domination in trees

open access: yesArs Combinatoria
We consider the eternal distance-2 domination problem, recently proposed by Cox, Meger, and Messinger, on trees. We show that finding a minimum eternal distance-2 dominating set of a tree is linear time in the order of the graph by providing a fast algorithm.
Clow, Alexander, van Bommel, Christopher
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

On irregular and antiregular domination in graphs [PDF]

open access: yesElectronic Journal of Mathematics, 2021
Akbar Ali, Gary Chartrand, Ping Zhang
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Domination Numbers in Graphs Resulting from Shackle Operations with Linkage of any Graph

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika)
The domination number is the number of dominating nodes in a graph that can dominate the surrounding connected nodes with a minimum number of dominating nodes. This domini number is denoted by γ(G). In this research, we will examine the domination number
Ilham Saifudin   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Domination in distance-hereditary graphs

open access: yesDiscrete Applied Mathematics, 2002
A linear time algorithm for the domination problem on distance-hereditary graphs is given.
Chang, M.S.   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy