Results 81 to 90 of about 263,414 (258)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

POWER DISTANCE AND VALUE ORIENTATIONS INFLUENCE ON OLIGARCHISM AND CRONY-SECTORS DEVELOPMENT IN MODERN ECOMNOMIC SYSTEMS

Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2017
The relationship between oligarchic economies and crony-sectors development, which includes industries with domination of rent-seeking behavior, is made.
V. Kozyuk, O. Dluhopolskyi
doaj   +1 more source

Fractional distance domination in graphs

Discussiones Mathematicae Graph Theory, 2012
Let G = (V,E) be a connected graph and let k be a positive integer with k ≤ rad(G). A subset D ⊆ V is called a distance k-dominating set of G if for every v ∈ V − D, there exists a vertex u ∈ D such that d(u,v) ≤ k. In this paper we study the fractional version of distance k-domination and related parameters.
Subramanian Arumugam, Kalimuthu Karuppasamy, Varughese Mathew   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Asymptotically Optimal Bounds for (t,2) Broadcast Domination on Finite Grids [PDF]

, 2018
Let $G=(V,E)$ be a graph and $t,r$ be positive integers. The \emph{signal} that a tower vertex $T$ of signal strength $t$ supplies to a vertex $v$ is defined as $sig(T,v)=max(t-dist(T,v),0),$ where $dist(T,v)$ denotes the distance between the vertices $v$
Randolph, Timothy W.
core   +2 more sources

Partitioning the vertex set of $G$ to make $G\,\Box\, H$ an efficient open domination graph

, 2016
A graph is an efficient open domination graph if there exists a subset of vertices whose open neighborhoods partition its vertex set. We characterize those graphs $G$ for which the Cartesian product $G \Box H$ is an efficient open domination graph when ...
Peterin, Iztok, Rall, Douglas F., Tepeh, Aleksandra, Šumenjak, Tadeja Kraner   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Long distance dominance andK + decays [PDF]

Zeitschrift für Physik C Particles and Fields, 1985
In an attempt to understand exclusiveK decays within a long distance framework, a simple and operative model for theK+ effective vertex is constructed and applied in the analysis of a few decay modes.
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source