Results 61 to 70 of about 4,831,666 (266)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Open Geosciences, 2017 In this paper, a location-based multiple point statistics method is developed to model a non-stationary reservoir. The proposed method characterizes the relationship between the sedimentary pattern and the deposit location using the relative central ...
Yin Yanshu, Feng Wenjie
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
SystemsThis paper introduces a novel decomposition method for analyzing production efficiency based on the Data Envelopment Analysis framework, addressing the limitations of traditional approaches that often fail to isolate the contributions of individual ...
Tingyang Huang +3 more
doaj +1 more source
Distance transform computation for digital distance functions
Theoretical Computer Science, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Strand, Robin, Normand, Nicolas
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Orientation, distance, regulation and function of neighbouring genes
Human Genomics, 2009 The sequencing of the human genome has allowed us to observe globally and in detail the arrangement of genes along the chromosomes. There are multiple lines of evidence that this arrangement is not random, both in terms of intergenic distances and ...
Gherman Adrian +2 more
doaj +1 more source
Measuring Spatial Accessibility of Health Care Providers - Introduction of a Variable Distance Decay Function within the Floating Catchment Area (FCA) Method. [PDF]
PLoS ONE, 2016 We integrated recent improvements within the floating catchment area (FCA) method family into an integrated 'iFCA`method. Within this method we focused on the distance decay function and its parameter.
Jan Bauer, David A Groneberg
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The vacuum functional at large distances [PDF]
Physics Letters B, 1995 11 pages ...
openaire +4 more sources