Results 61 to 70 of about 1,232,284 (259)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
On a relation between Szeged and Wiener indices of bipartite graphs [PDF]
Transactions on Combinatorics, 2012 Hansen et. al., using the AutoGraphiX software package, conjectured that the Szeged index Sz(G) and the Wiener index W(G) of a connected bipartite graph G with n ≥ 4 vertices and m ≥ n edges, obeys the relation Sz(G) − W(G) ≥ 4n − 8. Moreover, this bound
Ivan Gutman +3 more
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Tạp chí Khoa học Đại học Đà Lạt, 2013 A regular graph is a graph where each vertex has the same degree. A regular graph with vertices of degree k is called a k -regular graph or regular graph of degree k.
Đỗ Như An, Nguyễn Đình Ái
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Maximum Reciprocal Degree Resistance Distance Index of Unicyclic Graphs
Discrete Dynamics in Nature and Society, 2020 The reciprocal degree resistance distance index of a connected graph G is defined as RDRG=∑u,v⊆VGdGu+dGv/rGu,v, where rGu,v is the resistance distance between vertices u and v in G. Let Un denote the set of unicyclic graphs with n vertices.
Gai-Xiang Cai, Xing-Xing Li, Gui-Dong Yu
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Distance-Transitivity in Infinite Graphs
Journal of Combinatorial Theory, Series B, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Reciprocal degree distance of some graph operations [PDF]
Transactions on Combinatorics, 2013 The reciprocal degree distance (RDD), defined for a connected graph G as vertex-degreeweighted sum of the reciprocal distances, that is, RDD(G) = u,v∈PV(G) dG(u)+dG(v) dG(u,v) . The reciprocal degree distance is a weight version of the Harary index, just
Kannan Pattabiraman, M. Vijayaragavan
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source