Results 81 to 90 of about 601,118 (351)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Table S7 - Phylogenetic distance matrix. [PDF]
, 2019 Table S7 - Phylogenetic distance ...
Giannini, Norberto P +7 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Geographic and genetic distance matrix. [PDF]
, 2018 Geographic and genetic distance matrix.
Andrés Camacho-Alpízar (6107207) +2 more
core +1 more source
Preserving privacy of spatial distances using randomized geometric surface calculations
Journal of Spatial Information ScienceThis paper introduces and evaluates a novel method for privacy-preserving distance computations. The method is based on randomized geometric surface calculations and replaces coordinates with contextual variables representing information about the ...
Jonas Klingwort, Sarah Redlich
doaj +1 more source
Современные информационные технологии и IT-образование, 2019 Bioinformatics has two important problems for the study of evolutionary processes: calculating the distance between DNA sequences and restoring a matrix of distances sequences of different genomes when not all initial elements are known. Due to the large
Mikhail E. Abramyan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Supplemental_Data_8 Table 3 distance matrix [PDF]
, 2016 resulting distance matrix for the cluster ...
Marcos Gabriel Becerra (3267150) +3 more
core +1 more source
On the Distance Spectral Radius of Trees with Given Degree Sequence
Discussiones Mathematicae Graph Theory, 2020 We consider the problem of maximizing the distance spectral radius and a slight generalization thereof among all trees with some prescribed degree sequence.
Dadedzi Kenneth +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source