Results 91 to 100 of about 3,732,510 (304)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
On the Terminal Distance Matrix of Graphs
Iranian Journal of Mathematical Sciences and InformaticsSummary: Let \(G\) be a simple connected graph. The terminal distance matrix of \(G\) is the distance matrix between all pendant vertices of \(G\). In this paper, we study the terminal distance matrix and compute the characteristic polynomial of this matrix for some rooted trees.
openaire +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A distance geometry-based description and validation of protein main-chain conformation
IUCrJ, 2017 Understanding the protein main-chain conformational space forms the basis for the modelling of protein structures and for the validation of models derived from structural biology techniques. Presented here is a novel idea for a three-dimensional distance
Joana Pereira, Victor S. Lamzin
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
, 1996 This workshop item forms the first of a series of three presented jointly by the University of the West Indies and the International Extension College.
The Distance Education Center of the University of the West Indies and The International Extension College Training Link
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
A unified approach to protein domain parsing with inter-residue distance matrix. [PDF]
Bioinformatics, 2023 Zhu K, Su H, Peng Z, Yang J.
europepmc +1 more source
Bayesian Estimation of A Distance Functional Weight Matrix Model [PDF]
This paper considers the distance functional weight matrix in spatial autoregressive and spatial error models from a Bayesian point of view. We considered the Markov chain Monte Carlo methods to estimate the parameters of the models.
Kazuhiko Kakamu
core
, 2017 In distance education, a separation of roles between course design teams and student support teams are still characteristic of many specialized institutions.
Poellhuber, Bruno +9 more
core +1 more source