Results 101 to 110 of about 2,624,655 (295)

Proof of the Standard Quantum Limit for Monitoring Free-Mass Position

, 2010
The measurement result of the moved distance for a free mass m during the time t between two position measurements cannot be predicted with uncertainty smaller than sqrt{hbar t/2m}.
J. von Neumann, Seiji Kosugi, V. B. Braginsky, V. B. Braginsky   +3 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Using Time Drift of Cosmological Redshifts to find the Mass-Energy Density of the Universe

, 2010
In this paper we show that the mass-energy density of the Universe can be fully determined in terms of the cosmological redshifts, their time drifts and angular-diameter distance (observer area distance).
Araujo, M. E., Stoeger, W. R.
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

DISTANCE MEASURING DEVICE AND DISTANCE MEASURING METHOD

, 2018
A distance measuring device includes a light emission portion for emitting light; a light receiving portion for receiving measurement light that is emitted by the light emission portion and reflected by a measurement object, the light receiving portion comprising a plurality of pixels, each pixel having at least one light receiving portion and ...
Y. Matsui, K. Nakamuro, F. Villa, F. Zappa, R. Lussana   +4 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Direct strain and slope measurement using 3D DSPSI [PDF]

, 2013
This communication presents a new implementation of DSPSI. Its main features are 1. an advanced model taking into account the beam divergence, 2. the coupling with a surface shape measurement in order to generalize DSPSI to nonplanar surfaces 3.
Dandach, Wajdi, Molimard, Jérôme, Picart, Pascal   +2 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Indoor Inter-Robot Distance Measurement in Collaborative Systems

Advances in Electrical and Computer Engineering, 2010
This paper focuses on the problem of autonomous distance calculation between multiple mobile robots in collaborative systems. We propose and discuss two distinct methods, specifically developed under important design and functional constraints, such as
FILOTE, C., CHICIUDEAN, D., STANCOVICI, A., MICEA, M. V.   +3 more
doaj   +1 more source

Theoretical and experimental studies of magneto-aerodynamic drag and shock stand-off distance Progress report, 8 Jul. 1965 - 7 Jan. 1966 [PDF]

Magnetoaerodynamic drag and shock stand-off distance studies - free stream Mach number and specific heat ratio ...

core   +1 more source