Results 91 to 100 of about 2,624,655 (295)

X-ray luminescence computed tomography using a focused X-ray beam

, 2017
Due to the low X-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device (EMCCD) camera setup, the collimator based narrow beam X-ray luminescence computed tomography (XLCT) usually requires a ...
Li, Changqing, Lun, Michael C, Nguyen, Alex Anh-Tu, Zhang, Wei   +3 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

VLBI Astrometry of AGB Variables with VERA -- A Semiregular Variable S Crateris --

, 2008
We present a distance measurement for the semiregular variable S Crateris (S Crt) based on its annual parallax. With the unique dual beam system of the VLBI Exploration for Radio Astrometry (VERA) telescopes, we measured the absolute proper motion of a ...
Ando, Kazuma, Bushimata, Takeshi, Choi, Yoon Kyung, Hirota, Tomoya, Honma, Mareki, Imai, Hiroshi, Iwadate, Kenzaburo, Jike, Takaaki, Kameno, Seiji, Kameya, Osamu, Kamohara, Ryuichi, Kan-Ya, Yukitoshi, Kawaguchi, Noriyuki, Kijima, Masachika, Kim, Mi Kyoung, Kobayashi, Hideyuki, Kuji, Seisuke, Kurayama, Tomoharu, Maeda, Toshihisa, Manabe, Seiji, Maruyama, Kenta, Matsui, Makoto, Matsumoto, Naoko, Miyaji, Takeshi, Nagayama, Takumi, Nakagawa, Akiharu, Nakamura, Kayoko, Nyu, Daisuke, Oh, Chung Sik, Omodaka, Toshihiro, Oyama, Tomoaki, Pradel, Nicolas, Sakai, Satoshi, Sasao, Tetsuo, Sato, Katsuhisa, Sato, Mayumi, Shibata, Katsunori M., Suda, Hiroshi, Tamura, Yoshiaki, Tsushima, Miyuki, Ueda, Kousuke, Ueno, Yuji, Yamashita, Kazuyoshi   +42 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Self-Sensing Electromagnets for Robotic Tooling Systems: Combining Sensor and Actuator

Machines, 2016
A low-cost method, which integrates distance sensing functionality into a switched electromagnet by using a hybrid switching mode and current ripple measurements, is proposed.
Tobias Kamf, Johan Abrahamsson
doaj   +1 more source

Measuring the cosmic proper distance from fast radio bursts

, 2017
The cosmic proper distance $d_P$ is a fundamental distance in the Universe. Unlike the luminosity and angular diameter distances, which correspond to the angular size, the proper distance is the length of light path from the source to observer.
Wang, F. Y., Yu, H.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Distance of W3(OH) by VLBI annual parallax measurement

, 2004
The most powerful tool for measuring distances within our Galaxy is the annual parallax. We carried out phase-referencing VLBI observations of H$_{2}$O masers in the star forming region W3(OH) with respect to the extragalactic continuum source ICRF 0244 ...
A. Brunthaler, De Vicente, H. Imai, K. Hachisuka, K. M. Menten, M. Miyoshi, R. Colomer, T. Sasao, Y. Hagiwara   +8 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source