Results 61 to 70 of about 669,192 (265)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Research on Fiber-Optic Optical Coherence Ranging System Based on Laser Frequency Scanning Interferometry

open access: yesSensors
In this paper, a system for absolute distance measurement is proposed based on laser frequency scanning interferometry (FSI). The system utilizes a digitally tunable laser as the light source and employs synchronized pulses to drive an analog-to-digital ...
Yingjian Zhou, Yanhong Yuan, Meixue Su
doaj   +1 more source

PRG: A Distance Measurement Algorithm Based on Phase Regeneration

open access: yesSensors, 2018
With the booming development of the Internet of things (IoT) industry, the demand of positioning technology in various IoT application scenarios is also greatly increased. To meet the positioning requirements of the IoT application, we propose a distance
Yansong Cui, Di Zhu, Yanxu Liu
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Misalignment-Tolerant Planar Spiral Coil Pair Design for 13.56 MHz Inductive Coupling of Wireless Resistive Analog Passive Sensors

open access: yesSensors
Long-term daily-life body signal monitoring offers numerous advantages, such as timely response to health alerts, diseases monitoring, and reducing time and expenses related to clinical trials.
Babak Noroozi, Bashir I. Morshed
doaj   +1 more source

Distance Measurement and Object Detection System Based On Ultrasonic Sensor and XBee

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2020
In the past few years, research groups have focused on finding new solutions for objects detection in unknown and/or hazardous areas that can’t be accessed by humans, in order to create monitoring system that can ensure the safety and security of machine
Seda Üstün Ercan   +1 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Distance and Measurement in Domain Theory

open access: yesElectronic Notes in Theoretical Computer Science, 2001
AbstractWe investigate the notion of distance on domains. In particular, we show that measurement is a fundamental concept underlying partial metrics by proving that a domain in its Scott topology is partially metrizable only if it admits a measurement.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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