Results 111 to 120 of about 10,336,803 (378)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Comparison of distance measures in spatial analytical modeling for health service planning

open access: yesBMC Health Services Research, 2009
Background Several methodological approaches have been used to estimate distance in health service research. In this study, focusing on cardiac catheterization services, Euclidean, Manhattan, and the less widely known Minkowski distance metrics are used ...
Knudtson Merril L   +3 more
doaj   +1 more source

Statistical Test of Distance--Duality Relation with Type Ia Supernovae and Baryon Acoustic Oscillations

open access: yes, 2018
We test the distance--duality relation $\eta \equiv d_L / [ (1 + z)^2 d_A ] = 1$ between cosmological luminosity distance ($d_L$) from the JLA SNe Ia compilation (arXiv:1401.4064) and angular-diameter distance ($d_A$) based on Baryon Oscillation ...
Corasaniti, Pier-Stefano, Ma, Cong
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Complete next-to-leading-order study on the yield and polarization of Upsilon(1S,2S,3S) at the Tevatron and LHC

open access: yes, 2014
Based on nonrelativistic QCD factorization scheme, we present the first complete next-to-leading order study on the yield and polarization of Upsilon(1S,2S,3S) hadroproduction.
Gong, Bin   +3 more
core   +1 more source

Effect of timing jitter on time-of-flight distance measurements using dual femtosecond lasers.

open access: yesOptics Express, 2015
The cross correlation between a pair of femtosecond lasers with slightly different repetition rates enables high precision, high update rate time-of-flight (TOF) distance measurements against multiple targets.
Haosen Shi   +5 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

ORGANIZATION OF DISTANCE LEARNING FOR MEETING THE NEEDS OF MODERN STUDENTS

open access: yesІнформаційні технології і засоби навчання, 2015
The use of modern information technologies, including distance learning, significantly strengthened the traditional approaches to the educational process in higher education institutions.
Mariia A. Umryk
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

High-spin Metal Centres in Dipolar EPR Spectroscopy

open access: yesCHIMIA, 2018
The substitution of Mg2+ by Mn2+ in the bacterial DnaB helicase from Helicobacter pylori, an ATP:Mg2+-fuelled protein engine, allows electron paramagnetic resonance (EPR) spectroscopy to be performed on this system.
Katharina Keller   +6 more
doaj   +1 more source

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