Results 91 to 100 of about 5,398,404 (309)

ORGANIZATION OF DISTANCE LEARNING FOR MEETING THE NEEDS OF MODERN STUDENTS

open access: yesІнформаційні технології і засоби навчання, 2015
The use of modern information technologies, including distance learning, significantly strengthened the traditional approaches to the educational process in higher education institutions.
Mariia A. Umryk
doaj  

Comparison of distance measures in spatial analytical modeling for health service planning

open access: yesBMC Health Services Research, 2009
Background Several methodological approaches have been used to estimate distance in health service research. In this study, focusing on cardiac catheterization services, Euclidean, Manhattan, and the less widely known Minkowski distance metrics are used ...
Knudtson Merril L   +3 more
doaj   +1 more source

Computing the nearest euclidean distance matrix with low embedding dimensions [PDF]

open access: yes, 2013
Euclidean distance embedding appears in many high-profile applications including wireless sensor network localization, where not all pairwise distances among sensors are known or accurate.
Qi, Hou-Duo, Yuan, Xiaoming, Qi, Hou Duo
core   +1 more source

Absolute measurements (cm), of the distance between the main sulci and the occipital and frontal poles.

open access: yes, 2021
Absolute measurements (cm), of the distance between the main sulci and the occipital and frontal poles.
Rafael Bretas (11372647)   +5 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

How Distance Affects Gamma-Ray Burst Prompt Emission Measurements

open access: yesThe Astrophysical Journal
We investigated how gamma-ray burst (GRB) prompt emission measurements are affected by increasing distance to the source. We selected a sample of 26 bright GRBs with measured redshifts z   3) GRBs to a sample of 72 observed high- z bursts and found that ...
Michael J. Moss   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

High-spin Metal Centres in Dipolar EPR Spectroscopy

open access: yesCHIMIA, 2018
The substitution of Mg2+ by Mn2+ in the bacterial DnaB helicase from Helicobacter pylori, an ATP:Mg2+-fuelled protein engine, allows electron paramagnetic resonance (EPR) spectroscopy to be performed on this system.
Katharina Keller   +6 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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