Results 71 to 80 of about 754,637 (265)

Comparison of distance measures in spatial analytical modeling for health service planning

BMC Health Services Research, 2009
Background Several methodological approaches have been used to estimate distance in health service research. In this study, focusing on cardiac catheterization services, Euclidean, Manhattan, and the less widely known Minkowski distance metrics are used ...
Knudtson Merril L, Bertazzon Stefania, Shahid Rizwan, Ghali William A   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Relative-Localization Algorithm Using Incomplete Pairwise Distance Measurements for Underwater Applications

EURASIP Journal on Advances in Signal Processing, 2010
The task of localizing underwater assets involves the relative localization of each unit using only pairwise distance measurements, usually obtained from time-of-arrival or time-delay-of-arrival measurements. In the fluctuating underwater environment, a
Foo KaeY, Atkins PhilipR
doaj   +2 more sources

How Distance Affects Gamma-Ray Burst Prompt Emission Measurements

The Astrophysical Journal
We investigated how gamma-ray burst (GRB) prompt emission measurements are affected by increasing distance to the source. We selected a sample of 26 bright GRBs with measured redshifts z   3) GRBs to a sample of 72 observed high- z bursts and found that ...
Michael J. Moss, Amy Y. Lien, S. Bradley Cenko, Sylvain Guiriec, Craig B. Markwardt   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Field and Laboratory Investigation of USS3 Ultrasonic Sensors Capability for Non-contact Measurement of Pistachio Canopy Structure

Journal of Agricultural Machinery, 2015
Electronic canopy characterization to determine structural properties is an important issue in tree crop management. Ultrasonic and optical sensors are the most used sensors for this purpose. The objective of this work was to assess the performance of an
H Maghsoudi, S Minaei, B Ghobadian, H Masoudi   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

High-spin Metal Centres in Dipolar EPR Spectroscopy

CHIMIA, 2018
The substitution of Mg2+ by Mn2+ in the bacterial DnaB helicase from Helicobacter pylori, an ATP:Mg2+-fuelled protein engine, allows electron paramagnetic resonance (EPR) spectroscopy to be performed on this system.
Katharina Keller, Thomas Wiegand, Riccardo Cadalbert, Beat H. Meier, Anja Böckmann, Gunnar Jeschke, Maxim Yulikov   +6 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source