Results 161 to 170 of about 2,743,797 (328)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Global Determinants of COVID-19 Deaths: Lockdown Dates and Social Distancing Measures Mattered [PDF]

, 2020
Vincent J. Hooper
openalex  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Impact of distance measures in adaptive K-means clustering on load profiles and spatial patterns of distributed substations in Thailand. [PDF]

Sci Rep
Prompook T, Jittanon S, Phumeesut K, Termritthikun C, Ketjoy N, Chamsa-Ard W, Meesuk N, Madtharad C, Suriwong T.   +8 more
europepmc   +1 more source

Distance measured [PDF]

Nature, 1980
openaire   +2 more sources

A new distance measure for non-identical data with application to image classification [PDF]

, 2016
Muthukaruppan Swaminathan, Pankaj Yadav, Obdulio Piloto, Tobias Sjöblom, Ian Cheong   +4 more
openalex   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

MRI Distance Measures as a Predictor of Subsequent Clinical Status During the Preclinical Phase of Alzheimer's Disease and Related Disorders. [PDF]

Hum Brain Mapp
Zhang X, Caffo BS, Soldan A, Pettigrew C, Guray E, Davatzikos C, Morris JC, Benzinger TLS, Johnson SC, Masters CL, Fripp J, Resnick SM, Bilgel M, Kukull WA, Albert MS, Wang Z.   +15 more
europepmc   +1 more source

The effect of social distance measures on COVID-19 epidemics in Europe: an interrupted time series analysis. [PDF]

Geroscience, 2020
Vokó Z, Pitter JG.
europepmc   +1 more source