Results 31 to 40 of about 311,533 (268)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluation of Harmonics Impact on Digital Relays

Energies, 2018
This paper presents the concept of the impact of harmonic distortion on a digital protection relay. The aim is to verify and determine the reasons of a mal-trip or failure to trip the protection relays; the suggested solution of the harmonic distortion ...
Kinan Wannous, Petr Toman
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

RECENT TRENDS REGARDING DISTANCE PROTECTION A REVIEW [PDF]

Journal of Sustainable Energy, 2017
This paper is structured in six parts and aims to present actual trends regarding distance protection. In the first part is determined the importance of the topic and the requirement of using protections.
MESZAROS R.G., KILYENI ST., BARBULESCU C., MIHALCEA M.   +3 more
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Review on the Impact of Transmission Line Compensation and RES Integration on Protection Schemes

Energies
South Africa is currently experiencing an energy crisis because of a mismatch between energy supply and demand. Increasing energy demand necessitates the adequate operation of generation and transmission facilities to maintain the reliability of the ...
Ntombenhle Mazibuko, Kayode T. Akindeji, Katleho Moloi   +2 more
doaj   +1 more source

Investigating the effect of DG infeed on the effective cover of distance protection scheme in mixed-MV distribution network

International Journal of Renewable Energy Development, 2018
The environmental and economic features of renewable energy sources have made it possible to be integrated as Distributed Generation (DG) units in distribution networks and to be widely utilized in modern distribution systems.
Saad Muftah Saad, Naser El Naily, Faisal A. Mohamed   +2 more
doaj   +1 more source