Results 41 to 50 of about 1,644,928 (302)

Investigating the effect of DG infeed on the effective cover of distance protection scheme in mixed-MV distribution network

International Journal of Renewable Energy Development, 2018
The environmental and economic features of renewable energy sources have made it possible to be integrated as Distributed Generation (DG) units in distribution networks and to be widely utilized in modern distribution systems.
Saad Muftah Saad, Naser El Naily, Faisal A. Mohamed   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Review on the Impact of Transmission Line Compensation and RES Integration on Protection Schemes

Energies
South Africa is currently experiencing an energy crisis because of a mismatch between energy supply and demand. Increasing energy demand necessitates the adequate operation of generation and transmission facilities to maintain the reliability of the ...
Ntombenhle Mazibuko, Kayode T. Akindeji, Katleho Moloi   +2 more
doaj   +1 more source

Improved Faulted Phase Selection Algorithm for Distance Protection under High Penetration of Renewable Energies

Energies, 2020
The high penetration of renewable energies will affect the performance of present protection algorithms due to fault current injection from generators based on power electronics.
Eduardo Martínez Carrasco, María Paz Comech Moreno, María Teresa Villén Martínez, Samuel Borroy Vicente   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Building development and roads: implications for the distribution of stone curlews across the Brecks [PDF]

, 2013
Background: Substantial new housing and infrastructure development planned within England has the potential to conflict with the nature conservation interests of protected sites.
A Benítez-López, A Frid, A Møller, Adina Maya Merenlender, AP Møller, BM Bolker, CE Bealey, CF Dormann, CM Beale, D Liley, D Palomino, Durwyn Liley, EC Taylor, J Sharp, J Wallander, JC Underhill-Day, JK McKee, Joanna M. Sharp, JPW Scharlemann, JW Mallord, KP Burnham, LE Haskins, M Woods, M Yasue, MJ Whittingham, P McCullagh, PD Summers, R Reijnen, Ralph T. Clarke, RE Green, RE Green, RE Green, RE Green, Rhys E. Green, RI McDonald, RT Clarke, S Harris, TCF Day, W Halfwerk, Y Van Heezik   +39 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A comparison of the operational performance of different types of distance protection in new energy power transmission lines

Zhejiang dianli
Following a fault on an AC transmission line for new energy， the fault response of the new energy power supply can influence the operation of distance protection.
WANG Xingguo, YU Su
doaj   +1 more source