Results 111 to 120 of about 13,110,839 (301)
Keep Your Distance: Determining Sampling and Distance Thresholds in Machine Learning Monitoring
, 2022 Machine Learning~(ML) has provided promising results in recent years across different applications and domains. However, in many cases, qualities such as reliability or even safety need to be ensured. To this end, one important aspect is to determine whether or not ML components are deployed in situations that are appropriate for their application ...
Al-Harith Farhad +5 more
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Test of the Mean Distance Method for Forest Regeneration Assessment [PDF]
, 2014 A new distance-based estimator for forest regeneration assessment, the mean distance method, was developed by combining ideas and techniques from the wandering quarter method, T-square sampling and the random pairs method.
Hung, I-Kuai +4 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
, 2017 We present Keck/OSIRIS adaptive optics observations with 150-400 pc spatial sampling of 7 turbulent, clumpy disc galaxies from the DYNAMO sample ($0 ...
Abraham, R. +7 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
European Journal of Ecology, 2021 After becoming extinct approximately 250 years ago in the Palatinate Forest, the first Eurasian lynx (Lynx lynx) were reintroduced within this area in 2016, with 20 lynx reintroduced in the following five years. We observed the roe deer population within
Carolin Tröger +2 more
doaj
Investigating distance effects on environmental values: A choice modelling approach [PDF]
This paper describes a Choice Modelling experiment set up to investigate the relationship between distance and willingness to pay for environmental quality changes. The issue is important for the estimation and transfer of benefits.
Giovanni B. Concu
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Bi-Lipschitz Bijection between the Boolean Cube and the Hamming Ball
, 2013 We construct a bi-Lipschitz bijection from the Boolean cube to the Hamming ball of equal volume. More precisely, we show that for all even n there exists an explicit bijection f from the n-dimensional Boolean cube to the Hamming ball of equal volume ...
Benjamini, Itai +2 more
core +1 more source