Results 71 to 80 of about 1,899,876 (238)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Killer Plotting

open access: yesTidskrift för Litteraturvetenskap, 2017
Killer Plotting. Typological plot analysis based on distant readings of 113 contemporary swedish crime novels This article updates and extends Tzvetan Todorov’s classical typology of crime fiction from 1971 – where he separates plots driven by ...
Karl Berglund
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Enhancing Reading Comprehension for Secondary Students — Part II [PDF]

open access: yes, 2003
Enhancing Reading Comprehension for Secondary Students — Part II ...
The Meadows Center for Preventing Educational Risk   +1 more
core   +1 more source

Exploring explorers, travellers, and tourists: digital humanities approaches in North America and the United Kingdom

open access: yesMondes du Tourisme, 2023
Case studies in Britain, Canada, and the United States illustrate the wide range of projects using tools and techniques associated with the digital humanities that are expanding the scope and scale of enquiry in tourism and travel histories.
Kevin James, Gavin Hughes
doaj  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Czytanie dyfrakcyjne

open access: yesTeksty Drugie, 2023
The article overviews general principles of diffractive reading, an approach to literary studies inspired by Karen Barad’s agential realism. Barad’s concept is characterized by inclusiveness and interdisciplinarity; it does not represent a rigorous ...
Małgorzata Kowalcze
doaj  

Researching Culture through Big Data: Computational Engineering and the Human and Social Sciences

open access: yesSocial Sciences, 2018
The emergence of big data and data science has caused the human and social sciences to reconsider their aims, theories, and methods. New forms of inquiry into culture have arisen, reshaping quantitative methodologies, the ties between theory and ...
Teresa Duarte Martinho
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

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