Results 111 to 120 of about 356,474 (267)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

MSnet: Multi-Head Self-Attention Network for Distantly Supervised Relation Extraction

open access: yesIEEE Access, 2019
Distant supervision for relation extraction is a task of recognizing semantic relations between entities in a large amount of plain text weakly supervised by external knowledge bases, which can benefit many NLP applications, such as knowledge graph ...
Tingting Sun   +3 more
doaj   +1 more source

Pairwise Webpage Coreference Classification Using Distant Supervision

open access: yesProceedings of the 26th International Conference on World Wide Web Companion - WWW '17 Companion, 2017
A person or other entity is often associated with multiple URL endpoints on the web, motivating the task of determining whether a given pair of webpages is coreferent to a given entity. To strike a balance between unsupervised and supervised methods that require annotated data, we build a positive and unlabelled (PU) learning model, where we obtain ...
S. Subramanian   +3 more
openaire   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Sentence Interaction and Bag Feature Enhancement for Distant Supervised Relation Extraction

open access: yesAI
Background: Distant supervision employs external knowledge bases to automatically match with text, allowing for the automatic annotation of sentences.
Wei Song, Qingchun Liu
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Path-Based Attention Neural Model for Fine-Grained Entity Typing

open access: yes, 2018
Fine-grained entity typing aims to assign entity mentions in the free text with types arranged in a hierarchical structure. Traditional distant supervision based methods employ a structured data source as a weak supervision and do not need hand-labeled ...
Cai, Pengshan   +5 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Crowdsourcing Semantic Label Propagation in Relation Classification

open access: yes, 2018
Distant supervision is a popular method for performing relation extraction from text that is known to produce noisy labels. Most progress in relation extraction and classification has been made with crowdsourced corrections to distant-supervised labels ...
Aroyo, Lora   +2 more
core  

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