Results 61 to 70 of about 205,061 (335)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Distilling Policy Distillation

, 2019
The transfer of knowledge from one policy to another is an important tool in Deep Reinforcement Learning. This process, referred to as distillation, has been used to great success, for example, by enhancing the optimisation of agents, leading to stronger performance faster, on harder domains [26, 32, 5, 8].
Czarnecki, Wojciech Marian, Pascanu, Razvan, Osindero, Simon, Jayakumar, Siddhant M., Swirszcz, Grzegorz, Jaderberg, Max   +5 more
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

The Optimal Design of a Distillation System for the Flexible Polygeneration of Dimethyl Ether and Methanol Under Uncertainty

Frontiers in Energy Research, 2018
Two process designs for the separation section of a flexible dimethyl ether and methanol polygeneration plant are presented, as well as an optimization method which can determine the optimal design under market uncertainty quickly and to global ...
Thomas A. Adams II, Tokiso Thatho, Matthew C. Le Feuvre, Christopher L. E. Swartz   +3 more
doaj   +1 more source

A Narrative Review of Sulfur Compounds in Whisk(e)y

Molecules, 2022
The production process of whisky consists of malting, mashing, fermentation, distillation and maturation. Sulfur volatile compounds generated during this process have long attracted interest because they influence quality in general.
Akira Wanikawa, Toshikazu Sugimoto
doaj   +1 more source

Assisted Work Distillation [PDF]

Physical Review Letters, 2019
5+8 pages, to appear in Physical Review ...
Morris, Benjamin, Lami, Ludovico, Adesso, Gerardo   +2 more
openaire   +5 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Development of a Dynamic Modeling Approach to Simulate a Segmented Distillation Column for Flexible Operation

ChemEngineering, 2021
The need for flexible process equipment has increased over the past decade in the chemical industry. However, process equipment such as distillation columns have limitations that significantly restrict flexible operation.
Bastian Bruns, Henrik Fasel, Marcus Grünewald, Julia Riese   +3 more
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Hydrotreating of Sunan Candlenut (Reutealis trisperma Airy Shaw) Oil by Using NiMo-γAl₂O₃ as Renewable Energy

Indonesian Journal of Chemistry, 2019
Hydrotreating process of Sunan candlenut oil by using NiMo-γAl2O3 catalyst has been successfully investigated. Preparation of NiMo-γAl2O3 catalyst by using dipping impregnation method generated catalyst used for hydrotreating process.
Daliya Indra Setiawan, Tun Tedja Irawadi, Zainal Alim Mas’ud   +2 more
doaj   +1 more source