Results 61 to 70 of about 4,207,792 (288)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

SHORT syndrome: distinctive radiographic features

open access: yes, 1998
We report a boy with SHORT syndrome with distinctive radiographic features, comprising large epiphyses, gracile diaphyses and coned epiphyses, and demonstrate the evolution of the facies from the neonatal period to 9.5 years of ...
Morris, L., Haan, E.
core   +1 more source

The Characteristics of Korean Artists in Pronouncing English Words on Korean Reality Shows: A Generative Phonology Perspective

open access: yesRainbow: Journal of Literature, Linguistics and Culture
South Korea's cultural industry, known as the "Korean Wave" (Hallyu), has gained international popularity, particularly among younger generations, with its media attracting global attention.
Regina Galuh Prameswari Pratidina   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An Analysis of Consonant Pronunciation Errors by EFL Preschool Children (5-Years-Old): Distinctive Features Approach

open access: yesEnglish Franca: Academic Journal of English Language and Education
English students as second language learners must prioritize pronunciation. This study examines the pronunciation errors involved in the pronunciation of English consonants in Preschool Children (5 years), evaluates the analysis using a distinctive ...
Fransiska Inapaska Wuwur, Agus Subiyanto
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

INFLAMMASOME NLRP1 DISTINCTIVE FEATURES IN ATOPIC CONDITIONS

open access: yesМедицина в Кузбассе, 2023
The review article focuses on the NLRP1 inflammasome, which was discovered before the others but has been the least investigated. The emergence of the inflammasome in innate immunity container cells is an early event that precedes the development of any ...
Денис Сергеевич Загрешенко   +5 more
doaj  

Distinctive Features of Emotion Concepts.

open access: yes, 2021
Some theories of abstract word representation posit a role for affective information; however, little has been done to delineate how this holds for the class of emotion concepts relative to other types of abstract concepts. Work using distributional semantic models has shown that emotion words tend to co-occur with other highly affective words ...
Kelly, Alexandra E.   +1 more
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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