Results 61 to 70 of about 255,331 (256)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Distinctive Features of Emotion Concepts.
, 2021 Some theories of abstract word representation posit a role for affective information; however, little has been done to delineate how this holds for the class of emotion concepts relative to other types of abstract concepts. Work using distributional semantic models has shown that emotion words tend to co-occur with other highly affective words ...
Kelly, Alexandra E. +1 more
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Distinctive features of modern Japanese diplomatic service
Японские исследованияThe present study is an inquiry into the current state of Japanese diplomatic service and its distinctive features. The author makes use of the latest Japanese-language primary and secondary sources in his analysis that are rarely employed in Russian ...
V. A. Mozebakh
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
About the Creation of a Film Noir Canon [PDF]
452ºF, 2010 It is easier to establish a canon than to analyze its formation process. This article attempts to explain how the film noir canon was formed using the distinction between the corpus or catalog, the whole of the films, and the canon, the masterpieces ...
Sullà, Enric
doaj
DISTINCTIVE FEATURES OF HYDRODYNAMIC INVESTIGATION OF GAS-CONDENSATE WELLS
Известия высших учебных заведений: Нефть и газ, 2015 An equation is proposed for constructing a theoretical pressure build-up curve, which takes into account the effect of the well storage capacity, skin effect and presence of condensate in the bottomhole zone.
M. L. Karnaukhov +3 more
doaj +1 more source