Results 81 to 90 of about 254,635 (256)
A search for distinctive features of demand-led growth models
PSL Quarterly Review, 2014 This paper aims at a critical and constructive assessment of some extensions of Keynes’s analysis of effective demand to the long period and growth. A criticism is addressed to a single-cause interpretation of the demand-led growth models and to the ...
Sergio Parrinello
doaj +3 more sources
Distinctive features of modern Japanese diplomatic service
Японские исследованияThe present study is an inquiry into the current state of Japanese diplomatic service and its distinctive features. The author makes use of the latest Japanese-language primary and secondary sources in his analysis that are rarely employed in Russian ...
V. A. Mozebakh
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Electronics Letters, 2016 Curves and lines are geometrical, abstract features of an image. Whereas interest points are more limited, curves and lines provide much more information of the image structure. However, the research done in curve and line detection is very fragmented. The concept of scale space is not yet fused very well into curve and line detection.
B. Li, H. Li, U. Söderström
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
The SP Theory of Intelligence: Distinctive Features and Advantages
IEEE Access, 2016 This paper aims to highlight distinctive features of the SP theory of intelligence, realized in the SP computer model, and its apparent advantages compared with some AI-related alternatives.
James Gerard Wolff
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
On the Distinctive Features of the Modern Scientific Culture
Cultures of Science, 2019 Remarkable strides have been made in science ever since the scientific revolution in the 17th century, and the scientific community continues to prosper today.
Zhicong Shang PhD
doaj +1 more source