Results 101 to 110 of about 627,001 (273)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Two-channel Hyperspectral LiDAR with a Supercontinuum Laser Source

Sensors, 2010
Recent advances in nonlinear fiber optics and compact pulsed lasers have resulted in creation of broadband directional light sources. These supercontinuum laser sources produce directional broadband light using cascaded nonlinear optical interactions in ...
Ruizhi Chen, Juha Hyyppä, Teemu Hakala, Esa Räikkönen, Sanna Kaasalainen, Juha Suomalainen, Yuwei Chen   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Point-distinguishing chromatic index of the union of paths [PDF]

Czechoslovak Mathematical Journal, 2014
Let \(G\) be a simple graph. For an edge coloring of \(G\) and a vertex \(v\) of \(G\), let \(S(v)\) denote the set of colors of the edges incident to \(v\). An edge coloring of \(G\) is called a point-distinguishing general coloring, if \(S(u)\neq S(v)\) whenever \(u\neq v\).
openaire   +2 more sources

Development and validation of the VAE-NT index: a novel biomechanical parameter for distinguishing subclinical corneal abnormalities

Frontiers in Bioengineering and Biotechnology
PurposeThe aim of this study is to develop an index for distinguishing between very asymmetric ectasia with normal topography (VAE-NT) eyes and normal eyes, with good performance in validity, reliability, and predictive values.MethodsIn the training ...
Lanting Yang, Lanting Yang, Lanting Yang, Hui Xu, Hui Xu, Honghu Jiang, Jingyin Zhu, Shihao Chen, Shihao Chen   +8 more
doaj   +1 more source

Distinguishing number and distinguishing index of natural and fractional powers of graphs

, 2016
The distinguishing number (index) $D(G)$ ($D'(G)$) of a graph $G$ is the least integer $d$ such that $G$ has an vertex labeling (edge labeling) with $d$ labels that is preserved only by a trivial automorphism. For any $n \in \mathbb{N}$, the $n$-subdivision of $G$ is a simple graph $G^{\frac{1}{n}}$ which is constructed by replacing each edge of $G ...
Alikhani, Saeid, Soltani, Samaneh
openaire   +2 more sources

On the measurement of technological progress across countries [PDF]

We construct 14 alternative measures of technological progress for 19 OECD countries over the period 1970–2000, distinguishing between measures of productivity gains actually obtained in a given country (TFP growth, Malmquist index) and technological ...
Jakub Growiec
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source