Results 151 to 160 of about 445,292 (276)

Borel distinguishing number

open access: yes
In this paper, we study definable variants of the notion of the distinguishing number of a graph in descriptive set theoretic setting. We introduce the notion of the Borel distinguishing number of a Borel graph and provide examples that separate distinguishing number and Borel distinguishing number at various levels.
Bilge, Onur, Kaya, Burak
openaire   +2 more sources

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Distinguishing Number and Posets, Part II [PDF]

open access: yes, 2019
We introduce two distinguishing chromatic numbers of partially ordered sets, one based on incomparability and the other on comparability. This study has given us the opportunity to apply classic results in poset theory to obtain results about these ...
Collins, Karen
core  

DIALECTIC AND ITS ROLE IN ARISTOTLE’S POLITICAL MORPHOLOGY. THE CASE OF DISTINGUISHING OLIGARCHY AND DEMOCRACY

open access: yesStudia Universitatis Babeș-Bolyai. Philosophia, 2016
Dialectic and Its Role in Aristotle’s Political Morphology. The Case of Distinguishing Oligarchy and Democracy. Is the number of rulers an essential criterion in distinguishing democracy from oligarchy? This is an important issue tackled by Aristotle in
Iovan DREHE
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Distinguishing geometric graphs [PDF]

open access: yes, 2006
We begin the study of distinguishing geometric graphs. Let G be a geometric graph. An automorphism of the underlying graph that preserves both crossings and noncrossings is called a geometric automorphism.
Debra L. Boutin, Michael O. Albertson
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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