Results 51 to 60 of about 94,387 (307)
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2017 Hybrid incompatibilities are a common correlate of genomic divergence and a potentially important contributor to reproductive isolation. However, we do not yet have a detailed understanding of how hybrid incompatibility loci function and evolve within ...
Rachel E. Kerwin, Andrea L. Sweigart
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Identifying Mechanisms of AM-PM Distortion in Large Signal Amplifiers [PDF]
, 2015 We define the nonlinear dynamic phenomenon of AM to PM distortion and discuss different candidate mechanisms. Qualitative descriptions of this from of distortion are turned into expressions, and are applied to FET RF power amplifier described in the ...
Golara, Soheil
core
Distortion as a validation criterion in the identification of suspicious reviews [PDF]
, 2010 Assessing the trustworthiness of reviews is a key issue for the maintainers of opinion sites such as TripAdvisor. In this paper we propose a distortion criterion for assessing the impact of methods for uncovering suspicious hotel reviews in TripAdvisor ...
Guangyu Wu +7 more
core +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Comparison of joining efficiency and residual stresses in laser and laser hybrid welding [PDF]
, 2011 Laser welding is a high energy density process, which can produce welds with less energy input and thereby lower residual stress generation compared to arc welding processes.
Colegrove, Paul A. +9 more
core +1 more source
Metals, 2023 Although quenching is one of the most widely used heat treatments in the metal-mechanical industry to improve the mechanical properties of steels, it is also responsible for the generation of residual stress, distortion, and fractures in the treated ...
Carlos Puga-Patlán +4 more
doaj +1 more source
The Distortion of Prior-Independent b-Matching Mechanisms
CoRRIn a setting where $m$ items need to be partitioned among $n$ agents, we evaluate the performance of mechanisms that take as input each agent's \emph{ordinal preferences}, i.e., their ranking of the items from most- to least-preferred. The standard measure for evaluating ordinal mechanisms is the \emph{distortion}, and the vast majority of the ...
Ioannis Caragiannis +2 more
openaire +2 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source