Results 51 to 60 of about 2,286,559 (387)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Expert consensus on the precise classification and diagnosis of acute respiratory distress syndrome
Zhongguo Linchuang YixueAcute respiratory distress syndrome (ARDS) is a common critical illness in clinical practice, with a high mortality rate. Given the limited traditional treatment options for ARDS and the high heterogeneity among patients, most clinical trials have failed
Expert Group for Precise Classification and Diagnosis of Acute Respiratory Distress Syndrome
doaj +1 more source
Detecting financial distress [PDF]
, 2005 This paper examines two types of statistical tests, which are multiple discriminant analysis (MDA) and the logit model to detect financially distressed companies.
Abdullah, Nur Adiana Hiau +1 more
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
BMC Health Services ResearchBackground Mental health problems, self-harm and suicide are major public health concerns. Following national strategic commitments to improve the response and follow-up support for adults in Scotland presenting to frontline services in emotional ...
Ambrose J. Melson +6 more
doaj +1 more source
Teachers' coping strategies in mitigating remote learning-related distress during Covid-19 pandemic
Indonesian Journal of Social SciencesThe sudden shift to remote learning during the Covid-19 pandemic has brought much distress to teachers. Since the teachers are considered as the major force that facilitates the learning process, their well-being should be given importance.
Karen Margarette M. Doria +1 more
doaj +1 more source
Self-Compassion Therapy as a Transformative Intervention for Adolescent Girls’ Body Image [PDF]
Women’s Health BulletinBackground: Adolescent girls often struggle with negative body image, leading to rumination and distress. The objective of this investigation was to examine the potential of self-compassion therapy (SCT) to mitigate rumination and bolster distress ...
Fatemeh Masoudizadeh +3 more
doaj +1 more source
Rehabilitation of oncogynecological patients after antitumor therapy: ways of solution
Акушерство, гинекология и репродукция, 2020 The article provides a contemporary view on rehabilitation of oncogynecological patients. We considered physiological and psychological problems (surgical menopause and pain syndromes; impaired sexual function, distress, general intoxication, chronic ...
A. V. Vlasina +4 more
doaj +1 more source
The Walls Have Ears: Accessing Participant Narratives amid Silence, Secrecy, and Mistrust
Medicine Anthropology Theory, 2021 Eritreans have long been considered a close-knit community bound by the memorialisation of history and the preservation of cultural practices. My anthropological enquiry into the everyday experiences of mental distress among diasporic women revealed that
Brittney Shanel Mengistu
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source