Results 51 to 60 of about 1,044,921 (305)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Climate change distress and impairment in Germany

open access: yesFrontiers in Public Health
IntroductionClimate change has been widely recognized as one of the most challenging problems facing humanity and it imposes serious mental health threats.
Lars König   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Do social interactions explain ethnic differences in psychological distress and the protective effect of local ethnic density? A cross-sectional study of 226 487 adults in Australia [PDF]

open access: yes, 2013
Background: A frequently proposed, but under-researched hypothesis is that ethnic density benefits mental health through increasing social interactions.
Astell-Burt, Thomas (R16977)   +5 more
core   +1 more source

The relationship between distress tolerance and life satisfaction among young adults in Saudi Arabia

open access: yesFrontiers in Psychology
PurposeThis study examined the relationship between Distress Tolerance, defined as the individual’s ability to withstand psychological stress or endure negative emotions, and Life Satisfaction, the cognitive component of the individual’s subjective ...
Hala Abd Ellatif Elsayed   +1 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

The reported expression of pain and distress by people with an intellectual disability [PDF]

open access: yes, 2013
Aims and objectives. To explore the assumption that people with ID are unable to communicate effectively about pain by examining the extent to which they were reported as using language and behaviour that was readily understandable to others to ...
Purcell, Ann-Marie   +2 more
core   +1 more source

Validation of the distress thermometer among stroke survivors

open access: yes, 2012
National guidelines for stroke recommend that all patients entering rehabilitation are screened for mood disturbance using a validated measure. The first half of this thesis presents a literature review of 25 self-report screening measures for the ...
Gilson, Rachael
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Perancangan Sistem Pakar Fuzzy Multi-Attribute Decision Making Psychological Distress pada Generasi Millennials

open access: yesJurnal Eksplora Informatika, 2019
Psychological distress adalah keadaan subjektif yang dipresepsikan tidak menyenangkan. Setiap manusia tidak bisa menghindari dari gejala psychological distress yang meliputi depresi kecemasan ataupun stress, termasuk pada generasi millenials Generasi ...
Putri Taqwa Ningrum   +2 more
doaj   +1 more source

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