Results 61 to 70 of about 2,165,435 (385)
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
FEBS Letters, EarlyView.The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran +6 more
wiley +1 more source
A cross‐sectional study of distress: A cancer response
Nursing Open, 2020 Aim To describe the experience of distress in people with cancer of working age. Design A cross‐sectional study. Methods In this cross‐sectional study, patients (N = 168) with both ongoing (N = 56) and completed treatment (N = 105) completed the Distress
Hanna Ekman +3 more
doaj +1 more source
Interpersonal Behavior in Couple Therapy: Concurrent and Prospective Associations with Depressive Symptoms and Relationship Distress [PDF]
, 2018 Objective: This study investigated associations between couples’ interpersonal behavior, depressive symptoms, and relationship distress over the course of couple psychotherapy.
Knobloch-Fedders, Lynne M. +1 more
core +1 more source
Existential distress in cancer: Alleviating suffering from fundamental loss and change [PDF]
, 2018 A severe life threatening illness can challenge fundamental expectations about security, interrelatedness with others, justness, controllability, certainty, and hope for a long and fruitful life.
Kissane, David, Vehling, Sigrun
core +2 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Factors of emotional distress in lymphoma: A systematic review
Cancer Medicine, 2023 Objective Distress is prevalent among lymphoma patients/survivors. Current processes of distress identification rely on self‐reporting by patients/survivors, which may be limited by their willingness to report symptoms.
Kai Ping Tan +2 more
doaj +1 more source
Preemptive distress resolution through bank mergers [PDF]
, 2004 This paper suggests a motive for bank mergers that goes beyond alleged and typically unverifiable scale economies: preemtive resolution of banks´ financial distress.
Elsas, Ralf
core
Hospital nurses' moral distress and mental health during COVID‐19
Journal of Advanced Nursing, 2021 Aims To explore factors associated with nurses' moral distress during the first COVID‐19 surge and their longer‐term mental health. Design Cross‐sectional, correlational survey study.
E. Lake +8 more
semanticscholar +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
FEBS Open Bio, EarlyView.The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
BMC Pulmonary MedicineBackground SARS-CoV-2 is a systemic disease that affects endothelial function and leads to coagulation disorders, increasing the risk of mortality.
Rocío Nayeli Sánchez-Santillán +10 more
doaj +1 more source