Results 101 to 110 of about 4,253,766 (293)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The effect of the distributed test architecture on the power of testing [PDF]

open access: yes, 2008
Copyright @ 2008 Oxford University PressThere has been much interest in testing from finite-state machines (FSMs). If the system under test can be modelled by the (minimal) FSM N then testing from an (minimal) FSM M is testing to check that N is ...
Hierons, RM, Ural, H
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

dPQL: a lossless distributed algorithm for generalized linear mixed model with application to privacy-preserving hospital profiling. [PDF]

open access: yesJ Am Med Inform Assoc, 2022
Luo C   +8 more
europepmc   +1 more source

A methodology for deploying the max-sum algorithm and a case study on unmanned aerial vehicles

open access: yes, 2012
We present a methodology for the deployment of the max-sum algorithm, a well known decentralised algorithm for coordinating autonomous agents, for problems related to situational awareness.
Delle Fave, F. M.   +11 more
core   +1 more source

Agent-based decentralised coordination for sensor networks using the max-sum algorithm [PDF]

open access: yes, 2013
In this paper, we consider the generic problem of how a network of physically distributed, computationally constrained devices can make coordinated decisions to maximise the effectiveness of the whole sensor network. In particular, we propose a new agent-
Farinelli, A.   +10 more
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

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