Results 91 to 100 of about 533,224 (339)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Why things look the way they do: we live in a Cartesian grid of reified concepts

Frontiers in Psychology
The world we live in now is almost exclusively populated by things designed by minds to be understood by other minds. I argue here that: (1) Human environments now consist mainly of reified concepts, such as “chairs.” (2) These externalized concepts look
Guy C. Brown
doaj   +1 more source

Introduction: Multimodal interaction [PDF]

, 2005
That human social interaction involves the intertwined cooperation of different modalities is uncontroversial. Researchers in several allied fields have, however, only recently begun to document the precise ways in which talk, gesture, gaze, and aspects ...
Sidnell, J., Stivers, T.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A comparative web survey of audiences’ cognitions for plays distributed through the internet and at the theater.

, 2022
Sumire Hirota, Tomomi Takezawa
openalex   +4 more sources

Artificial intelligence as a cognitive partner: a developmental framework for human–AI co-regulation in learning

Frontiers in Developmental Psychology
Over the past decade, artificial intelligence (AI) has undergone a tremendous shift from a highly technical instrument to a household learning, problem-solving, and decision-making cognitive aid.
Pooja S, Josephine Joseph, Marin Jose, Anitha S. M, Revati N, Jeena Joseph   +5 more
doaj   +1 more source

On the modeling of neural cognition for social network applications

, 2017
In this paper, we study neural cognition in social network. A stochastic model is introduced and shown to incorporate two well-known models in Pavlovian conditioning and social networks as special case, namely Rescorla-Wagner model and Friedkin-Johnsen ...
Cvetkovic, Vladimir, Johansson, Karl H., Molinari, Marco, Wei, Jieqiang, Wu, Junfeng   +4 more
core   +1 more source

Compositional Distributional Cognition

, 2016
We accommodate the Integrated Connectionist/Symbolic Architecture (ICS) of [32] within the categorical compositional semantics (CatCo) of [13], forming a model of categorical compositional cognition (CatCog). This resolves intrinsic problems with ICS such as the fact that representations inhabit an unbounded space and that sentences with differing tree
Al-Mehairi, Yaared, Coecke, Bob, Lewis, Martha   +2 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Digital Organizational Resilience in Latin American MSMEs: Entangled Socio-Technical Systems of People, Practices, and Data

Systems
This study develops a systemic framework to conceptualize digital organizational resilience in micro, small, and medium-sized enterprises (MSMEs) as an emergent property of entangled socio-technical systems. Building on theories of distributed cognition,
Alexander Sánchez-Rodríguez, Reyner Pérez-Campdesuñer, Gelmar García-Vidal, Yandi Fernández-Ochoa, Rodobaldo Martínez-Vivar, Freddy Ignacio Alvarez-Subía   +5 more
doaj   +1 more source