Results 101 to 110 of about 127,580 (297)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Understanding emergency medical dispatch in terms of distributed cognition: a case study

open access: yes, 2006
Emergency medical dispatch (EMD) is typically a team activity, requiring fluid coordination and communication between team members. Such working situations have often been described in terms of distributed cognition (DC), a framework for understanding ...
Dominic Furniss   +3 more
core  

Semantic Modulation of Temporal Attention: Distributed Control and Levels of Abstraction in Computational Modelling [PDF]

open access: yes, 2006
This paper presents a computational exploration of how meaning modulates temporal attention. This has been explored within the context of Barnard et al's key-distractor Attentional Blink (AB) and proposes a mechanism by which attention is captured by ...
Su, Li, Barnard, Philip, Bowman, Howard
core  

Musicality as Distributed Cognition in a Dance Studio

open access: yesmethaodos.revista de ciencias sociales, 2016
Musicality in dance does not need music. ¿How is musicality apparent in the dance studio, and to what extent is a social construct? We define musicality as a social skill.
Dafne Muntanyola-Saura
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Playing with pattern. Aesthetic communication as distributed cognition

open access: yesAisthesis, 2019
This article’s main thesis is that aesthetic communication has evolved from animal social play to forms of extraordinary complexity such as traditional arts, helping to preserve and transfer survival oriented information in a preverbal, or embodied form.
José Ignacio Contreras
doaj   +1 more source

Distribution of cognitive load in Web search [PDF]

open access: yesJournal of the American Society for Information Science and Technology, 2010
AbstractThe search task and the system both affect the demand on cognitive resources during information search. In some situations the demands may become too high for a person. This article has a three‐fold goal. First, it presents and critiques methods to measure cognitive load.
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

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