Results 61 to 70 of about 130,788 (258)

Finite Difference and Chebyshev Collocation for Time-Fractional and Riesz Space Distributed-Order Advection–Diffusion Equation with Time-Delay

Fractal and Fractional
In this paper, we have established a numerical method for a class of time-fractional and Riesz space distributed-order advection–diffusion equation with time-delay.
Fang Wang, Yuxue Chen, Yuting Liu
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Dynamics of 2D Navier-Stokes equations with Rayleigh's friction and distributed delay

Electronic Journal of Differential Equations, 2019
This article concerns the long time dynamics of a 2D incompressible Navier-Stokes equation with Rayleigh's friction and distributed delay. Under appropriate assumptions on the external force and delay term, we obtain global well-posedness in new phase
Yadi Wang, Xin-Guang Yang, Xingjie Yan
doaj  

Blow-up of solutions for a system of nonlocal singular viscoelastic equations with sources and distributed delay terms

Boundary Value Problems
In this paper, we investigate a scenario concerning a coupled nonlocal singular viscoelastic equation with sources and distributed delay terms. By establishing suitable conditions, we have proved that a finite-time blow-up occurs in the solution.
Abdelbaki Choucha, Mohammad Shahrouzi, Rashid Jan, Salah Boulaaras   +3 more
doaj   +1 more source

Video caching and scheduling with edge cooperation

Digital Communications and Networks
In this paper, we explore a distributed collaborative caching and computing model to support the distribution of adaptive bit rate video streaming.
Zhidu Li, Fuxiang Li, Tong Tang, Hong Zhang, Jin Yang   +4 more
doaj   +1 more source

Global asymptotic stability of stochastic BAM neural networks with distributed delays and reaction–diffusion terms

Journal of Computational and Applied Mathematics, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
P. Balasubramaniam 0001, C. Vidhya
openaire   +2 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source