Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Pseudo almost periodic solutions for quaternion-valued cellular neural networks with discrete and distributed delays. [PDF]
Meng X, Li Y.
europepmc +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Distributed consensus and optimization under communication delays
—We study the effects of communication delays in distributed consensus and optimization algorithms. We propose two ways to model delays. First, assuming each edge of a communication network has a fixed delay, we characterize the consensus value exactly ...
Konstantinos I. Tsianos +1 more
core +1 more source
Adaptive Synchronization of Fractional-Order Complex-Valued Neural Networks with Discrete and Distributed Delays. [PDF]
Li L, Wang Z, Lu J, Li Y.
europepmc +1 more source
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
A Consensus Approach to Distributed Convex Optimization in Multi-Agent Systems [PDF]
In this thesis we address the problem of distributed unconstrained convex optimization under separability assumptions, i.e., the framework where a network of agents, each endowed with local private convex cost and subject to communication constraints ...
Filippo Zanella, Zanella, Filippo
core
Pseudo almost periodic solutions for shunting inhibitory cellular neural networks with continuously distributed delays. [PDF]
Lu Y, Ji D.
europepmc +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source

