Results 121 to 130 of about 377,929 (357)

Ice thickness estimation method of overhead line based on distributed optical fiber temperature sensing

open access: diamond, 2022
Xiaoming Zou   +5 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Ridge Estimators for Distributed Lag Models [PDF]

open access: yes
The paper explains how the Almon polynominal lag specification can be made stochastic in two different ways - one suggested by Shiller and another following the lines of Lindley and Smith.
G.S. Maddala
core  

Distributed Blind Estimation Over Sensor Networks

open access: yesIEEE Access, 2017
Distributed estimation, where a set of nodes collaboratively estimate some parameters of interest from noisy measurements, has received much attention in both science and engineering. Recent studies mainly focus on distributed non-blind or training-based
Ying Liu, Lili Li
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Dalton Medal Lecture: How far can we go in distributed hydrological modelling? [PDF]

open access: yes, 2001
This paper considers distributed hydrological models in hydrology as an expression of a pragmatic realism. Some of the problems of distributed modelling are discussed including the problem of nonlinearity, the problem of scale, the problem of ...
Beven, K. J., Keith Beven, Beven*, K.
core  

Estimation of round trip time in distributed real time system architectures

open access: yes, 2013
Real-time distributed systems may sometimes utilize a centralized node to manage and coordinate the exchange of information resulting from network conditions, such as users being behind firewall or proxy servers.
Andrew D. Maxwell   +5 more
core   +1 more source

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