Results 71 to 80 of about 646,449 (284)

Application of probabilistic PCR5 Fusion Rule for Multisensor Target Tracking

, 2007
This paper defines and implements a non-Bayesian fusion rule for combining densities of probabilities estimated by local (non-linear) filters for tracking a moving target by passive sensors. This rule is the restriction to a strict probabilistic paradigm
Celeste, Francis, Dambreville, Frederic, Dezert, Jean, Kirchner, Alois, Smarandache, Florentin   +4 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Distributed Large-Scale Information Filtering

, 2014
We study the problem of distributed resource sharing in peer-to-peer networks and focus on the problem of information filtering. In our setting, subscriptions and publications are specified using an expressive attribute-value representation that supports both the Boolean and Vector Space models.
Tryfonopoulos, C., Idreos, S., Koubarakis, M., Raftopoulou, P.   +3 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Blind-Matched Filtering for Speech Enhancement with Distributed Microphones

Journal of Electrical and Computer Engineering, 2012
A multichannel noise reduction and equalization approach for distributed microphones is presented. The speech enhancement is based on a blind-matched filtering algorithm that combines the microphone signals such that the output SNR is maximized.
Sebastian Stenzel, Jürgen Freudenberger
doaj   +1 more source

Likelihood Consensus and Its Application to Distributed Particle Filtering

, 2012
We consider distributed state estimation in a wireless sensor network without a fusion center. Each sensor performs a global estimation task---based on the past and current measurements of all sensors---using only local processing and local ...
Djuric, Petar M., Hlawatsch, Franz, Hlinka, Ondrej, Rupp, Markus, Sluciak, Ondrej   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Distributed Mining for Content Filtering Function Based on Simulated Annealing and Gene Expression Programming in Active Distribution Network

IEEE Access, 2017
As an important part of the Internet of Energy, a complex access environment, flexible access modes and a massive number of access terminals, dynamic, and distributed mass data in an active distribution network will bring new challenges to the security ...
Song Deng, Changan Yuan, Jiquan Yang, Aihua Zhou   +3 more
doaj   +1 more source