FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Distributed Model Predictive Consensus via the Alternating Direction Method of Multipliers [PDF]
, 2012 We propose a distributed optimization method for solving a distributed model predictive consensus problem. The goal is to design a distributed controller for a network of dynamical systems to optimize a coupled objective function while respecting state ...
Lygeros, John, Summers, Tyler H.
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A Fast Fault Detection Scheme for Power Converters In Distributed Generation Systems
Eletrônica de Potência, 2012 In this paper, a fault detection algorithm based on voltage disturbances is proposed and analyzed. This method observes the voltage characteristics instead of the current amplitude, that is the most common approach in power distribution electrical ...
Gustavo M. S. Azevedo +3 more
doaj +1 more source
Optimization techniques applied for optimal planning and integration of renewable energy sources based on distributed generation: Recent trends [PDF]
, 2020 Abdurrahman Shuaibu Hassan +2 more
openalex +1 more source
Active local distribution network management for embedded generation [PDF]
, 2005 Traditionally, distribution networks have been operated as passive networks with uni-directional power flows. With the connection of increasing amounts of distributed generation, these networks are becoming active with power flowing in two directions ...
White, Sara
core
Distributed Generation as Voltage Support for Single Wire Earth Return Systems [PDF]
, 2004 Key issues for distributed generation (DG) inclusion in a distribution system include operation, control, protection, harmonics, and transients. This paper analyzes two of the main issues: operation and control for DG installation.
Kashem, Mohammad, Ledwich, Gerard
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Distributed Generation and Load Modeling in Microgrids [PDF]
, 2023 Mohammad AlMuhaini +2 more
openalex +1 more source
Maximising revenue for non-firm distributed wind generation with energy storage in an active management scheme [PDF]
, 2013 The connection of high penetrations of renewable generation such as wind to distribution networks requires new active management techniques. Curtailing distributed generation during periods of network congestion allows for a higher penetration of ...
Barbour, Edward +3 more
core +1 more source