Results 121 to 130 of about 8,663,531 (404)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Multivariate generalized Pareto distributions: parametrizations, representations, and properties [PDF]

open access: yesarXiv, 2017
Multivariate generalized Pareto distributions arise as the limit distributions of exceedances over multivariate thresholds of random vectors in the domain of attraction of a max-stable distribution. These distributions can be parametrized and represented in a number of different ways.
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Status of the current parabolic dish technology [PDF]

open access: yes, 1981
Vu-graphs are presented that show that point focus distributed receiver distributed generation systems are cost competitive with current utilities. System cost caveats and typical power module costs are described.
Sumrall, C.
core   +1 more source

A Generalization of the Hypergeometric Distribution

open access: yesSultan Qaboos University Journal for Science [SQUJS], 2000
 In this paper we introduce a modification of the hypergeometric distribution that caters for the case when the sampling scheme favours the inclusion of units of one of the two types involved, as opposed to the hypergeometric distribution under which all samples are equally likely.
Ali Benmerzouga, E.K. Elsheikh
openaire   +3 more sources

Likelihood Assignment for Out-of-Distribution Inputs in Deep Generative Models is Sensitive to Prior Distribution Choice [PDF]

open access: yesarXiv, 2019
Recent work has shown that deep generative models assign higher likelihood to out-of-distribution inputs than to training data. We show that a factor underlying this phenomenon is a mismatch between the nature of the prior distribution and that of the data distribution, a problem found in widely used deep generative models such as VAEs and Glow.
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Study on business models of distributed generation in China

open access: yesGlobal Energy Interconnection, 2018
Along with the implementation of electricity sales-side reform and incremental power distribution investment liberalization under China’s new round of electricity market reform, the main subjects of distributed generation investment, construction, and ...
Hui Yu   +5 more
doaj  

On the Generalized Arcsine Probability Distribution with Bounded Support [PDF]

open access: yesarXiv, 2015
Properties of the beta functions are investigated. We define the generalized arcsine probability distribution with bounded support. The properties of the beta functions prove some results for this distribution.
arxiv  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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