Results 121 to 130 of about 7,723,373 (378)

The generalized Gompertz distribution

open access: yesApplied Mathematical Modelling, 2013
AbstractThis paper deals with a new generalization of the exponential, Gompertz, and generalized exponential distributions. This distribution is called the generalized Gompertz distribution (GGD). The main advantage of this new distribution is that it has increasing or constant or decreasing or bathtub curve failure rate depending upon the shape ...
Ahmad M. Alshamrani   +2 more
openaire   +2 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

The Photovoltaic Generation and its Energy Contribution and Demand Shifting at the Center Headquarters of the Federal University of Technology - Paraná - Campus Curitiba

open access: yesBrazilian Archives of Biology and Technology, 2018
Distributed photovoltaic (PV) generation is characterized by the application of several small power plants in urban centers. This form of energy deserves special mention due to the possibility of installation in existing areas such as roofs and facades ...
Juliana D’Angela Mariano   +1 more
doaj   +1 more source

Overview of three-phase inverter topologies for distributed generation purposes [PDF]

open access: yes, 2010
The increasing presence of single-phase distributed generators and unbalanced loads in the electric power system may lead to unbalance of the three phase voltages, resulting in increased losses and heating.
De Kooning, Jeroen   +5 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Distributed generation powered by smart grids

open access: yesDyna
Smart grids are conceived as a system to optimally manage the set of means that are part of the electricity grid to achieve adequate performance in the distributed generation system in the supply of quality electricity.
Alcira Magdalena Vélez-Quiroz   +5 more
doaj   +1 more source

Robust efficient distributed RSA-key generation [PDF]

open access: bronze, 1998
Yair Frankel   +2 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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