Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Correction: Parallel operated hybrid Arithmetic-Salp swarm optimizer for optimal allocation of multiple distributed generation units in distribution networks. [PDF]
PLoS One, 2023 Anjum ZM +4 more
europepmc +1 more source
Solar thermal power systems point-focusing thermal and electric applications projects. Volume 1: Executive summary [PDF]
The activities of the Point-Focusing Thermal and Electric Applications (PETEA) project for the fiscal year 1979 are summarized. The main thrust of the PFTEA Project, the small community solar thermal power experiment, was completed.
Marriott, A.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Efficient Methodology for Detection and Classification of Short-Circuit Faults in Distribution Systems with Distributed Generation. [PDF]
Sensors (Basel), 2022 Santos ADS +4 more
europepmc +1 more source
Mitigating the Impact of Distributed Generations on Relay Coordination Using Fault Current Limiters
, 2021 Meisam Ansari, Mostafa Ansari
openalex +2 more sources
The Emergence of Distributed Generation Units in Europe. [PDF]
Dans cet article de recherche, nous nous intéressons à la relation entre innovation et organisation industrielle dans le secteur de l’électricité. Avec le processus de dérégulation en Europe, le rôle des nouvelles technologies de production apparaît ...
Méritet, Sophie
core
A generalization of the Rice's distribution
Revista Técnica de la Facultad de Ingeniería, 2011 The author defines a generalization of the density \[ f_R(r)=\frac{r}{\sigma^I_0}(\frac{Ar} {\sigma}) exp^{(\frac{r^2+A^2}{2\sigma^2})}, \] \(r>0\), called here Rice's density, as: \[ f(a,\alpha,\nu; v) = H v^{\alpha}I_{\nu}(av) exp^{(\frac{a^2+v^2}{2})}, \] where \(I_{\nu}\) is the \({\nu}\) th-order Bessel function, and the parameters verify \(a>0\),
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source