Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Learning Observer-Based Sensor Fault-Tolerant Control of Distributed Generation in an Islanded Microgrid for Bus Voltage Stability Enhancement. [PDF]
Sensors (Basel), 2022 Mao J, Yin C, Zhang X, Wu A, Zhang X.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Parallel operated hybrid Arithmetic-Salp swarm optimizer for optimal allocation of multiple distributed generation units in distribution networks. [PDF]
PLoS One, 2022 Anjum ZM +4 more
europepmc +1 more source
Identifying options for regulating the coordination of network investments with investments in distributed electricity generation [PDF]
This paper analyses two effects of the current Dutch regulation on the system operators of the electricity network and on teh decentralised generators of electricity, and suggests a number of improvements in the tariff regulation.
Eva Niesten
core
Optimal distributed generation planning in active distribution networks considering integration of energy storage [PDF]
, 2018 Yang Li +5 more
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Spotted hyena optimizer algorithm for capacitor allocation in radial distribution system with distributed generation and microgrid operation considering different load types. [PDF]
Sci Rep, 2021 Naderipour A +6 more
europepmc +1 more source