Results 11 to 20 of about 56,857 (169)

Modeling the evolution of natural cliffs subject to weathering. 2, Discrete element approach [PDF]

, 2011
The evolution of slopes subjected to weathering has been modeled by assuming Mohr-Coulomb behavior and by using a numerical approach based on the discrete element method (DEM).
Crosta, Giovanni B., Utili, Stefano
core   +1 more source

A New Model for Void Coalescence by Internal Necking [PDF]

, 2010
A micromechanical model for predicting the strain increment required to bring a damaged material element from the onset of void coalescence up to final fracture is developed based on simple kinematics arguments.
Becker, R., Becker, R., Benzerga, A.A., Benzerga, A.A., Benzerga, A.A., Brown, L.M., Enakoutsa, K., F. Scheyvaerts, Gao, X., Gologanu, M., Huber, G., Lassance, D., Lassance, D., Leblond, J.-B., Marini, B., Mear, M., Mudry, F., P.R. Onck, Pardoen, T., Pardoen, T., Ragab, A.R., Scheyvaerts, F., Steglich, D., T. Pardoen, Thomason, P.F., Thomason, P.F., Tvergaard, V., Tvergaard, V., Worswick, M.J.   +28 more
core   +5 more sources

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Micromechanically Based Constitutive Relations for Polycrystalline Solids [PDF]

, 1983
A basic method to estimate the overall mechanical response of solids which contain periodically distributed defects is presented. The method estimates the shape and growth pattern of voids periodically distributed over the grain boundaries in a viscous ...
Iwakuma, T., Nemat-Nasser, S.
core   +1 more source

Stochastic approximation of score functions for Gaussian processes [PDF]

, 2013
We discuss the statistical properties of a recently introduced unbiased stochastic approximation to the score equations for maximum likelihood calculation for Gaussian processes.
Anitescu, Mihai, Chen, Jie, Stein, Michael L.   +2 more
core   +1 more source

A Skills Gap Analysis of Farmer Directors of US Farmer Cooperatives

Agribusiness, EarlyView.
ABSTRACT Boards of directors are vital to firm performance and are an integral part of the decision‐making process of any business. Several studies have been conducted that observe corporate or nonprofit board characteristics, skills, and the board's connection to firm performance.
Jody S. Herchenbach, Brian C. Briggeman, Jason S. Bergtold, Aleksan Shanoyan, Sarah A. Low, Brandi Miller   +5 more
wiley   +1 more source

Exploring the Impact of Meat Alternative Labeling Regulations on the U.S. Meat Consumption Patterns

Agribusiness, EarlyView.
ABSTRACT The global demand for conventional meat continues to rise, but it is also associated with substantial environmental and health challenges. In response, meat alternatives have gained popularity, sparking debates over meat alternative labeling regulations. This study investigates the effects of meat alternative labeling regulations in the United
Jeong Hun Ji, Sang Hyeon Lee
wiley   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

PEER Testbed Study on a Laboratory Building: Exercising Seismic Performance Assessment [PDF]

, 2005
From 2002 to 2004 (years five and six of a ten-year funding cycle), the PEER Center organized the majority of its research around six testbeds. Two buildings and two bridges, a campus, and a transportation network were selected as case studies to ...
Beck, James L., Chang, Stephanie E., Chaudhuri, Samit Ray, Comerio, Mary C., Falit-Baiamonte, Anthony, Holmes, William T., Hutchinson, Tara, Konstantinidis, Dimitrios, Lee, Tae-Hyung, Makris, Nicos, Mosalam, Khalid, Porter, Keith A., Shaikhutdinov, Rustem, Smith, Ryan, Somerville, Paul, Stallmeyer, John C.   +15 more
core  

Size effects and idealized dislocation microstructure at small scales: predictions of a phenomenological model of Mesoscopic Field Dislocation Mechanics: Part I

, 2005
A Phenomenological Mesoscopic Field Dislocation Mechanics (PMFDM) model is developed, extending continuum plasticity theory for studying initial-boundary value problems of small-scale plasticity.
Acharya, Amit, Roy, Anish
core   +1 more source