Results 161 to 170 of about 2,576,787 (284)

Leadership Challenges In Today’s Academia [PDF]

open access: yes
Starting from the anecdotic hypothesis that “leading academics is like trying to herd cats”, the paper reviews the main challenges and barriers to present academic leadership.
Dima, Alina Mihaela   +4 more
core  

Sustaining Distributed Leadership: Lessons Learned from a Case Study of Delaware Middle Schools

open access: yes, 2014
The purpose of this study is to provide a thick, rich description of distributed leadership practices at a suburban Delaware school district, to explore, per Spillane, Halverson, & Diamond (2004), the hows and whys of building-level distributed ...
Bariexca, Damian Nicholas.
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Distributed leadership in South African schools: possibilities and constraints

open access: yesSouth African Journal of Education, 2011
Before 1994 South African teachers in general, but more specifically women teachers, were effectively excluded from fulfilling meaningful roles as leaders at school level.
Clarence G Williams
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The Impact of Distributed Leadership on Teacher’s Job Satisfaction

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
Teacher job satisfaction is an important factor in improving the quality of education. This research aims to examine the impact of distributed leadership on teacher job satisfaction. Distributed leadership is an approach where leadership responsibilities
Syamsir Alam   +3 more
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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