Results 91 to 100 of about 131,942 (264)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Solid-Phase Reference Baths for Fiber-Optic Distributed Sensing. [PDF]

Sensors (Basel), 2022
Thomas CK, Huss JM, Abdoli M, Huttarsch T, Schneider J.   +4 more
europepmc   +1 more source

Random‐access distributed fiber sensing

Laser & Photonics Reviews, 2012
AbstractOptical sensing offers an attractive solution to the societal concern for prevention of natural and human‐generated threats and for efficient use of natural resources. The unprecedented properties of optical fibers make them ideal for implementing a ‘nervous system’ in structural health monitoring: they are small, low‐cost and electrically and ...
Zadok A., Antman Y., Primerov N., Denisov A., Sancho J., Thevenaz L.   +5 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analytical Modeling Tool for Design of Hydrocarbon Sensitive Optical Fibers

Sensors, 2017
Pipelines are the main transportation means for oil and gas products across large distances. Due to the severe conditions they operate in, they are regularly inspected using conventional Pipeline Inspection Gages (PIGs) for corrosion damage.
Khalil Al Handawi, Nader Vahdati, Oleg Shiryayev, Lydia Lawand   +3 more
doaj   +1 more source

Optical Fiber Distributed Sensing Network for Thermal Mapping in Radiofrequency Ablation Neighboring a Blood Vessel. [PDF]

Biosensors (Basel), 2022
Sametova A, Kurmashev S, Ashikbayeva Z, Blanc W, Tosi D.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Digital Twin for Civil Engineering Systems: An Exploratory Review for Distributed Sensing Updating. [PDF]

Sensors (Basel), 2022
Bado MF, Tonelli D, Poli F, Zonta D, Casas JR.   +4 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Fiber-Optic Distributed Sensing Network for Thermal Mapping of Gold Nanoparticles-Mediated Radiofrequency Ablation. [PDF]

Biosensors (Basel), 2022
Sametova A, Kurmashev S, Ashikbayeva Z, Amantayeva A, Blanc W, Atabaev TS, Tosi D.   +6 more
europepmc   +1 more source