Results 51 to 60 of about 6,319,999 (278)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
EURASIP Journal on Wireless Communications and Networking, 2005 We consider the case of two correlated sources, and . The correlation between them has memory, and it is modelled by a hidden Markov chain. The paper studies the problem of reliable communication of the information sent by the source over an additive ...
Ser Javier Del +2 more
doaj +2 more sources
A Distributed Source Coding Framework for Bandwidth-Efficient Neural Network Parameter Updates
IEEE AccessNeural networks have helped solve numerous problems and create applications in various fields in the past few years. In order for the neural networks to perform well, the number of parameters has had to grow considerably in size.
Annabella Chou
doaj +1 more source
AN AUTOMATED BOTTOM UP HYDROLOGIC CODING SYSTEM FOR DENDRITIC RIVER SYSTEM [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 The hydrologic coding of a dendritic river system can be used to indicate the stream order and spatial-structure features of a river system. However, most conventional hydrologic coding systems use a top down (i.e., from the source to the estuary ...
Z. X. Dai, C. M. Li, P. D. Wu, Y. Yin
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
"Graph Entropy, Network Coding and Guessing games" [PDF]
, 2007 We introduce the (private) entropy of a directed graph (in a new network coding sense) as well as a number of related concepts. We show that the entropy of a directed graph is identical to its guessing number and can be bounded from below with the number
RIIS, SM
core +4 more sources
Entropy, 2019 Consider a symmetric multivariate Gaussian source with ℓ components, which are corrupted by independent and identically distributed Gaussian noises; these noisy components are compressed at a certain rate, and the compressed version is leveraged to ...
Yizhong Wang +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Entropy, 2023 Distributed video coding (DVC) is based on distributed source coding (DSC) concepts in which video statistics are used partially or completely at the decoder rather than the encoder.
Shahzad Khursheed +4 more
doaj +1 more source