Results 71 to 80 of about 1,346,974 (288)

Distributed data storage systems with opportunistic repair [PDF]

IEEE INFOCOM 2014 - IEEE Conference on Computer Communications, 2014
The reliability of erasure-coded distributed storage systems, as measured by the mean time to data loss (MTTDL), depends on the repair bandwidth of the code. Repair-efficient codes provide reliability values several orders of magnitude better than conventional erasure codes.
Aggarwal, Vaneet, Tian, Chao, Vaishampayan, Vinay A., Chen, Yih-Farn R.   +3 more
openaire   +2 more sources

Cost-bandwidth tradeoff in distributed storage systems [PDF]

Computer Communications, 2010
8 pages,8 ...
Akhlaghi, Soroush, Kiani, Abbas, Ghanavati, Mohammad Reza   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Construction of Optimal Locally Repairable Codes of Triangular Association Schemes

Shanghai Jiaotong Daxue xuebao
As a new erasure code for distributed storage systems, locally repairable codes (LRCs) can effectively realize the reliable and efficient storage of massive data.
WANG Jing, LI Jinghui, YANG Jiarong, WANG E
doaj   +1 more source

Non-Strategic Capacity Withholding from Distributed Energy Storage within Microgrids Providing Energy and Reserve Services

Energies, 2020
Microgrids have the potential to provide security and flexibility to power systems through the integration of a wide range of resources, including distributed energy storage, usually in the form of batteries.
Fernando J. Lanas, Francisco J. Martínez-Conde, Diego Alvarado, Rodrigo Moreno, Patricio Mendoza-Araya, Guillermo Jiménez-Estévez   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Ceph-based storage strategy for big gridded remote sensing data

Big Earth Data, 2021
When using distributed storage systems to store gridded remote sensing data in large, distributed clusters, most solutions utilize big table index storage strategies. However, in practice, the performance of big table index storage strategies degrades as
Xinyu Tang, Xiaochuang Yao, Diyou Liu, Long Zhao, Li Li, Dehai Zhu, Guoqing Li   +6 more
doaj   +1 more source

Effects of Storage Heterogeneity in Distributed Cache Systems

, 2018
In this work, we focus on distributed cache systems with non-uniform storage capacity across caches. We compare the performance of our system with the performance of a system with the same cumulative storage distributed evenly across the caches.
Karamchandani, Nikhil, Moharir, Sharayu, Reddy, Kota Srinivas   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source