Results 91 to 100 of about 250,794 (316)

Research and Implementation of Massive Design Documents on Distributed Storage ＆ Load Balancing

Dianxin kexue, 2013
The most suitable system architecture was presented, based on the distributed storage and load balancing, after the analysis and comparison of the technology of massive design documents in distributed storage.
Liliang Su, Yunfu Wang, Bin Hou
doaj   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A generic storage API

, 2011
Submitted to ACSC 2004 This work was supported by EPSRC grant GR/R45154 "Bulk Storage of XML Documents"We present a generic API suitable for provision of highly generic storage facilities that can be tailored to produce various individually customised ...
Dearle, Alan, Kirby, Graham, Zirintsis, Evangelos, Morrison, Ron   +3 more
core  

Research on accelerating Ceph storage performance with SmartNICs

Dianzi Jishu Yingyong
This paper focuses on the issue of limited multi-core parallel scalability caused by thread lock contention mechanisms in the architecture of the Ceph storage system's Object Storage Device (OSD).
Liu Baoqin, Luo Xiangzheng, Lin Mao, Wang Qinya, Lan Lisha   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Dynamic erasure coding decision for modern block-oriented distributed storage systems

, 2016
Modern block-oriented distributed storage systems like Hadoop distributed file system have proliferated in this era of big data and cloud computing. These systems feature block-level replication in which their files are partitioned into equalsized blocks 
이윤준, 안후영, 이경하
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Balancing latency and availability in geo-distributed cloud data stores

, 2013
Modern web applications face stringent requirements along many dimensions including latency, scalability, and availability. In response, several geo-distributed cloud storage systems have emerged in recent years.
Tawarmalani, Mohit, P N, Shankaranarayanan, Sivakumar, Ashiwan, Rao, Sanjay   +3 more
core  

Performance Guarantees for Distributed Reachability Queries [PDF]

, 2012
In the real world a graph is often fragmented and distributed across different sites. This highlights the need for evaluating queries on distributed graphs.
Wang, Xin, Fan, Wenfei; id_orcid, Wu, Yinghui   +2 more
core